- 中文名称
Anti-Human Follistatin like-protein 1/FSTL1
- 英文名字
- Anti-Human Follistatin like-protein 1/FSTL1
- 供应商
- ReliaTech
- 产品货号
- 101-M422
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Follistatin-like 1 (FSL1 or FSTL1), also known as FRP (follistatin-related protein), Flik (follistatin-like), and TSC36 (TGFβ1stimulated clone 36), is a secreted 45-55 kDa extracellular glycoprotein belonging to the BM40/ SPARC/Osteonectin family. The human FSTL1 cDNA encodes 308 amino acids (aa), including a 20 aa signal sequence, a cysteinerich Follistatin (EGF and kazal-like) domain, two apparently non-functional EF hand calciumbinding motifs, and a von Willebrand Factor C homology domain. Mature human FSTL1 shares 94%, 95%, 98%, and 99% aa identity with mouse, rat, bovine, and equine FSTL1, respectively. FSTL1 was first identified as a TGF-beta-induced protein from a mouse osteoblast cell line (4). It is ubiquitously expressed in early mouse development, but is mainly mesenchymal later in development. In humans, FSTL1 is a common rheumatoid arthritis autoantigen. It is reported to be either proinflammatory due to promoting inflammatory cytokine secretion, or to prevent autoimmune arthritis by inhibiting matrix metalloproteinase (MMP) and prostaglandin expression. In muscle and heart, it appears to be protective and promotes endothelial cell functions such as revascularization after ischemia, probably due to promoting expression and activation of the protein kinase AKT1.
- 应用类型
- WB
- 免疫原
- 该Anti-Human Follistatin like-protein 1/FSTL1的详细信息查看ReliaTech提供的产品说明书。
- 来源宿主
- 该Anti-Human Follistatin like-protein 1/FSTL1的详细信息查看ReliaTech提供的产品说明书。
- 反应性
- 该Anti-Human Follistatin like-protein 1/FSTL1的详细信息查看ReliaTech提供的产品说明书。
- 保存建议
- 该Anti-Human Follistatin like-protein 1/FSTL1的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- 其他
- ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
