VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
应用类型
WB, IHC, ELISA
免疫原
该Anti-Human VEGFR-2/KDR的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human VEGFR-2/KDR的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human VEGFR-2/KDR的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human VEGFR-2/KDR的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
