The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.
应用类型
WB
免疫原
该Anti-Human Common beta chain的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human Common beta chain的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human Common beta chain的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human Common beta chain的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
