Eotaxin3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin2 loci. Eotaxin3/ CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin3/ CCL26 expression can also be detected in various tissues. The expression of Eotaxin 3/CCL26 in vascular endothelial cells has been shown to be upregulated by IL13 and IL4. Eotaxin3/ CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. Eotaxin3/ CCL26 induces calcium flux in eosinophils as well as in CCR3transfected cells. Eotaxin 3/ CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands.
应用类型
ELISA, WB, N
免疫原
该Anti-Human Eotaxin-3的详细信息查看ReliaTech提供的产品说明书。
来源宿主
Mouse
反应性
该Anti-Human Eotaxin-3的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human Eotaxin-3的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
