- 中文名称
8-iso Prostaglandin E2-d4 (500 ug)
- 英文名字
- 8-iso PGE2-d4|8-epi PGE2-d4, 8-iso Prostaglandin E2-d4, 9-oxo-11.alpha.,15S-dihydroxy-(8.beta.)-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
- 供应商
- Cayman
- 产品货号
- 10011321-500
- 产品报价
- ￥27104/500 ug
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- 8-iso Prostaglandin E2-d4 -8-iso PGE2-d4) contains four deuterium atoms at the hydroxyethyl 3, 3 ,4, and 4 positions. It is intended for use as an internal standard for the quantification of 8-iso PGE2 by GC- or LC-mass spectrometry. 8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 uM, respectively. When infused into the renal artery of the rat at a concentration of 4 mg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.
- 产品描述
- An internal standard for the quantification of 8-iso PGE2 by GC- or LC-MS
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
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