- 中文名称
Akt(人重组蛋白)WB即用型对照 (1 ea)
- 英文名字
- Akt -human recombinant) Western Ready Control (1 ea)
- 供应商
- Cayman
- 产品货号
- 10010079-1
- 产品报价
- ￥714/1 ea
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- Akt is a serine/threonine kinase that has been implicated in cell survival, cell proliferation, insulin signaling, and is often found to be over expressed in many kinds of human tumors. There are three isoforms of Akt -Akt1 Akt2, and Akt3) that differ in their cellular location and expression levels. Activated PI3K catalyzes the formation of PI-3,4)P2 and PI-3,4,5)P3. These phospholipids act as second messengers to recruit Akt to the plasma membrane through binding of the PH domain. Akt then becomes phosphorylated on threonine 308 and serine 473 to become a fully active kinase. Akt is down regulated by the serine/threonine protein phosphatases PP2A and .lambda.PP.
- 序列
- 来源宿主
- 溶解建议
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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