- 中文名称
PCSK9 WB即用型对照 (1 ea)
- 英文名字
- PCSK9 Western Ready Control (1 ea)
- 供应商
- Cayman
- 产品货号
- 10009567-1
- 产品报价
- ￥714/1 ea
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Proprotein convertase subtilisin kexin 9 -PCSK9) is a member of the subtilisin serine protease family with an important role in low density lipoprotein -LDL) metabolism. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in low density lipoprotein cholesterol levels. PCSK9 overexpression in wild-type mice doubles the plasma total cholesterol, possibly through acceleration of the degradation of the LDL receptor. PCSK9 mRNA is detected in various tissues such as liver, kidney, lung, spleen, jejunum, ileum, colon, and muscles with the highest expression in the liver. Human PCSK9 precursor is 692 amino acid in length with an estimated molecular weight of 74 kDa. This proprotein is self-cleaved to form a mature protein at around 63 kDa in the golgi.
- 序列
- 来源宿主
- 溶解建议
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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