- 中文名称
9-Z),11-E),13-E)-Octadecatrienoic Acid ethyl ester (50 mg)
- 英文名字
- 供应商
- Cayman
- 产品货号
- 10008350-50
- 产品报价
- ￥7840/50 mg
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- 9-Z),11-E),13-E)-Octadecatrienoic Acid ethyl ester -.alpha.-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. .alpha.-ESA is metabolized and converted to conjugated linoleic acid -9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, .alpha.-ESA induced apoptosis through up-regulation of GADD45, p53, and PPAR.gamma.. In DLD-1 cells supplemented with .alpha.-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 uM. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 uM for different isoforms of the enzymes. .alpha.-ESA ethyl ester is a neutral, more lipid soluble form of the free acid.
- 产品描述
- .alpha.-ESA ethyl ester is a neutral, more lipid soluble form of the free acid.
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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