- 中文名称
Gestrinone (5 g)
- 英文名字
- Gestrinone, 13-ethyl-17.alpha.-hydroxy-18,19-dinorpregna-4,9,11-trien-2-yn-3-one
- 供应商
- Cayman
- 产品货号
- 10006488-5
- 产品报价
- ￥47530/5 g
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Endometriosis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosis. It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone -LH) and follicle-stimulating hormone -FSH), thus reducing estrogen synthesis. It also binds to androgen -AR), progesterone -PR), and estrogen -ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin. Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively. These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.
- 产品描述
- Endometriosis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosis.{12994} It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone -LH) and follicle-stimulating hormone -FSH), thus reducing estrogen synthesis.{12994} It also binds to androgen -AR), progesterone -PR), and estrogen -ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin.{13002} Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively.{12992} These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.{12992}
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
