Negative control for protein kinase C (PKC) inhibitors. S6K inhibitor. Necrosis inhibitor. A cell-permeable negative control compound for protein kinase C inhibition studies (IC50 > 100uM). Blocks the activation of p70s6k/p85s6kin vivo (IC50 = 8uM). A cell-permeable negative control compound for protein kinase C inhibition studies (IC50 >100uM). Blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6kin vivo (IC50 8uM).Synonyms:Ro 31-6045, BIM V; 2,3-bis(1H-Indol-3-yl)-N-methylmaleimideCAS No:113963-68-1Molecular Formula:C21H15N3O2Molecular Weight:341.4Appearance:Redish-orange solidPurity:≥98% (NMR)Storage and Stability:Short-term Storage: +4°CLong-term Storage: -20°CStable for at least 2 years after receipt when stored at -20°C.
产品形式
该产品为橙红色固体。
保存建议
接收到Bisindolylmaleimide V (Ro 31-6045, BIM V)产品后,置于4°C/-20°C温度下保存。