Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17RA receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells. Recombinant rat IL-17AF is a non-glycosylated, disulfide-linked heterodimer, containing one IL-17A subunit and one IL-17F subunit. The dimer has a total of 269 amino acids, with total molecular weight of 30.7 kDa.
序列
该Rat Interleukin-17AF Heterodimer Recombinant Protein - 012-001-V56-0025的详细信息查看Rockland提供的产品说明书。
来源宿主
该Rat Interleukin-17AF Heterodimer Recombinant Protein - 012-001-V56-0025的详细信息查看Rockland提供的产品说明书。
溶解建议
Restore with deionized water (or equivalent)
保存建议
Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
