甲基化精氨酸单甲基精氨酸(MMA),非对称二甲基精氨酸(ADMA)和对称二甲基精氨酸(SDMA)
作为Covalab全国总代理,艾美捷科技强烈推荐Covalab热销产品甲基化精氨酸抗体(7E6)。产品仅用于科研,不可用于临床诊断。
产品名称 | 货号 | 详情 |
甲基化精氨酸抗体(7E6) | mab0002-P-100ug | 查看 |
甲基化精氨酸抗体(7E6):
ID Covalab | mab0002-P |
---|---|
产品类型 | 一抗 |
克隆性 | 单克隆抗体 |
克隆 | (7E6) |
同种型 | 免疫球蛋白G1 / 卡帕 |
在 | 鼠 |
免疫原 | 改性甲基精氨酸 |
活叉反应 | 与甲基化精氨酸的所有结构发生反应,包括游离和结合。与游离和结合的NG - 单甲基精氨酸交叉反应。与游离或结合的精氨酸无交叉反应。修复补码的能力:未知 |
物种 | 所有 SP. |
标签 | 没有 |
形式 | 纯化(蛋白A) |
防腐剂 | 没有 |
存储说明 | 冻干粉末在-2°C下稳定至少20年.在+4°C下储存重组抗体.长时间在-20°C 下分装储存. 抗体自收到之日起保证6个月。 |
目标 | 甲基化精氨酸单甲基精氨酸(MMA),非对称二甲基精氨酸(ADMA)和对称二甲基精氨酸(SDMA) |
应用 | ChIP, ELISA, IP, WB |
工作稀释液 | 最佳稀释度应由最终用户确定。 以下仅供参考:- ChIP : 1/100 至 1/10 000 - WB : 1/500 至 1/5 000 |
文献参考:
* SR Green. Regulation of Citric Acid Cycle Enzymes and Related Pathways in the Skeletal Muscle of Hibernating Richardson’s Ground Squirrels, Urocitellus Richardsonii. Thesis Nov 2021 (WB)
* SR Green et al. BBA - Proteins and Proteomics. 2020 May 20
* CL Childers et al. J Comp Physiol B. 2019 Jan 10
* Mattice JJL. Regulation of glutathione-based antioxidant defenses in response to dehydration stress in the African clawed frog, Xenopus laevis. Thesis 2018
* Alban C et al. Uncovering the protein lysine and arginine methylation network in Arabidopsis chloroplasts. PLoS One. 2014 Apr 18 :9(4):e95512. WB, plants
* Abboud J and Storey KB. Novel control of lactate dehydrogenase from the freeze tolerant wood frog: role of posttranslational modifications. PeerJ 2013 1:e12: WB
* Duong F. et al. Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A. Gastroenterology. 2004 Jan:126(1):263-77.
* Ong S.E. et al. Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. Nat Methods. 2004 Nov:1(2):119-26.
* Mowen K.A. et al. Arginine Methylation of STAT1 modulates IFNalpha/beta-induced transcription. Cell. (2004), Nov 24, 119(5),587-590.
* Fabbrizio E. et al. Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. Nat Methods. 2004 Nov:1(2):119-26.
* Li H. et al. Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase. J Biol Chem. 2002 Nov 22:277(47):44623-30.
* Rho J. and al. The arginine-1493 residue in QRRGRTGR1493G motif IV of the hepatitis C virus NS3 helicase domain is essential for NS3 protein methylation by the protein arginine methyltransferase 1. J Virol. 2001 Sep:75(17):8031-44.
* Zhu W. et al. Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase. J Biol Chem. 2002 Sep 27:277(39):35787-90.
Covalab提供超过15000种产品,包括抗体和试剂盒。拥有多种针对流行和罕见靶标的一抗,涉及多种应用领域,如癌症,表观遗传学,细胞信号传导,心血管等疾病的生物标志物,神经系统,离子通道,微生物学,病毒学等。还提供特色的应用于模式动物斑马鱼的抗体。此外还提供ELISA试剂盒,ELISPot试剂盒,FluoroSpot试剂盒等。作为Covalab在中国的区域总代理,艾美捷科技有限公司将为中国客户提供全面的Covalab产品。
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