肠道病毒71-VP1(EV71-VP1)蛋白高品质抗体

人肠道病毒71型(EV71)是手足口病的主要病原体

        肠病毒71型（enterovirus 71，EV71）病毒是一种引起手足口病的主要致病病原体，更可导致无菌性脑膜炎，脑干脑炎，以及脊髓灰质炎样麻痹等多种神经系统相关疾病。EV71是小RNA病毒科肠道病毒属成员，病毒基因组由大约7408个核苷酸组成的单股正链RNA，具有侵染性。病毒外壳由四个外壳蛋白（VP1、VP2、VP3和VP4）组成，其中外壳蛋白VP1 为最重要的抗原决定簇。

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       EV71-VP1抗体实验应用：

        《1》EV71-VP1抗体WB检测：     

       《2》EV71-VP1抗体ELISA检测抗体：

       已发表文献：

•        Fibronectin facilitates EV71 infection by mediating its entry.

He QQ, Ren S, Xia ZC, Cheng ZK, Peng NF, Zhu Y.J Virol. 2018 Feb 21. [Epub ahead of print]   

•        HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.

Ge M, Luo Z, Qiao Z, Zhou Y, Cheng X, Geng Q, Cai Y, Wan P, Xiong Y, Liu F, Wu K, Liu Y, Wu J.J Immunol. 2017 Nov 1;199(9):3280-3292. doi: 10.4049/jimmunol.1700376. Epub 2017 Sep 27.   

•        Berberine inhibits enterovirus 71 replication by downregulating the MEK/ERK signaling pathway and autophagy.

Wang H, Li K, Ma L, Wu S, Hu J, Yan H, Jiang J, Li Y.Virol J. 2017 Jan 11;14(1):2.   

•        A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71.

Liou AT, Wu SY, Liao CC, Chang YS, Chang CS, Shih C1.Sci Rep. 2016 Aug 8;6:31151.   

•        Early growth response-1 facilitates enterovirus 71 replication by direct binding to the viral genome RNA.

Song Y, Cheng X, Yang X, Zhao R, Wang P, Han Y, Luo Z, Cao Y, Zhu C, Xiong Y, Liu Y, Wu K, Wu JInt J Biochem Cell Biol. 2015 Feb 24;62:36-46. doi: 10.1016/j.biocel.2015.02.012.   

•        PolyC-Binding Protein 1 Interacts with 5'-Untranslated Region of Enterovirus 71 RNA in Membrane-Associated Complex to Facilitate Viral Replication.

Luo Z, Dong X, Li Y, Zhang Q, Kim C, Song Y, Kang L, Liu Y, Wu K, Wu JPLoS One. 2014 Jan 29;9(1):e87491. doi: 10.1371/journal.pone.0087491. eCollection 2014.   

•        Human enterovirus 71 uncoating captured at atomic resolution.

Lyu K, Ding J, Han JF, Zhang Y, Wu XY, He YL, Qin CF, Chen RJ Virol. 2014 Mar;88(6):3114-26. doi: 10.1128/JVI.03029-13. Epub 2013 Dec 18.   

•        The highly conserved 5' untranslated region as an effective target towards the inhibition of Enterovirus 71 replication by unmodified and appropriate 2'-modified siRNAs.

Deng JX, Nie XJ, Lei YF, Ma CF, Xu DL, Li B, Xu ZK, Zhang GC.J Biomed Sci. 2012 Aug 13;19:73.   

•        Enterovirus 71 Disrupts Interferon Signaling by reducing the Interferon Receptor I.

Lu J, Yi L, Zhao J, Yu J, Chen Y, Lin MC, Kung HF, He ML.J Virol. 2012 Jan 18. [Epub ahead of print]   

•        Viral kinetics of Enterovirus 71 in human abdomyosarcoma cells.

       Lu J, He YQ, Yi LN, Zan H, Kung HF, He ML.World J Gastroenterol. 2011 Sep 28;17(36):4135-42.     艾美捷科技与国内外优秀的生物试剂供应商保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：Abbkine、Merck Millipore、Origene、AAT Bioquest、Cayman Chemical、Abnova 、Biovision、ProSpec、Hycult Biotech 、Equitech-Bio、Trevigen、Alomone Labs、Epigentek、ImmunoReagents 、Jackson、SouthernBiotech、US Biological 、Caisson Labs等，可以在第一时间为用户提供最前沿的专业资讯、完备的产品及物流服务。