Jena bioscience--Pseudo-UTP：RNA合成中的非天然尿苷酸三磷酸

Jena bioscience--Pseudo-UTP：Ψ-UTP 假尿苷-5'-三磷酸钠盐

Cat. No. Amount

NU-1139S 10 ?l (100 mM)

NU-1139L 5 x 10 ?l (100 mM)

艾美捷Pseudo-UTP：

货号：NU-1139L

运输：使用凝胶包装运输

储存条件：需在-20°C下储存，可以短期（累计不超过1周）暴露在室温下。

保质期：自交货日期起12个月

分子式：C9H15N2O15P3（游离酸）

分子量：484.14 g/mol（游离酸）

精确质量：483.97 g/mol（游离酸）

CAS号：1175-34-4

纯度：≥ 95%（高效液相色谱法）

形态：水溶液

颜色：无色至微黄

浓度：100 mM - 110 mM

pH值：7.5 ±0.5

溶解性：可溶于水

光谱特性：最大吸收波长约为265 nm ±2 nm，摩尔吸光系数7.9 L mmol^-1 cm^-1（Tris-HCl pH 7.5）

相关产品：

高产T7 RNA合成试剂盒，#RNT-101

Pseudo-UTP参考文献：

Anderson et al. (2012) Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK. Gene Ther. doi: 10.1038/gt.2012.5.

Green et al. (2012) Activation of autoreactive B cells by endogenous TLR7 and TLR3 RNA ligands. J. Biol. Chem. 287 (47):39789.

Karikó et al. (2012) Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin. Mol Ther. 20 (5):984.

Warren et al. (2012) Feeder-free derivation of human induced pluripotent stem cells with messenger RNA. Sci Rep. 2:657.

Anderson et al. (2011) Nucleoside modifications in RNA limit activation of 2’-5’-oligoadenylate synthetase and increase resistance to cleavage by RNase L. Nucleic Acids Research. 39 (21):9329.

Karikó et al. (2011) Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein encoding mRNA. Nucleic Acids Research. 39 :e142.