人IFN-γ在大肠杆菌中表达的人干扰素γ重组蛋白。
1、II型干扰素
2、非糖基化多肽二聚体
PBL Assay Science/艾美捷人IFN-γ(PBL-11500-1)规格:
配方 在含有 0.1% 牛血清白蛋白 (BSA) 的磷酸盐缓冲盐水 (PBS) 中冷冻提供
分子量 16.8 千达
源 从大肠杆菌中表达的人 T 淋巴细胞中获得的人 cDNA
纯度 > 95% 通过考马斯蓝
内毒素水平 < 1 EU/μg 染色的 SDS-PAGE
生物 活性 使用细胞病变抑制测定法对伴有脑心肌炎病毒 (EMCV) 的人肺癌细胞系 A549 进行测量
存储 用于将完整活动存储保留在 -70oC或以下,避免反复冻融循环
PBL Assay Science人IFN-γ引用文献:
Crawford, J.D., et al., (2023), "The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE", JCI Insight., e169344, PMID: 37733447, DOI: 10.1172/jci.insight.169344
Fung, S. K., et al.,(2022), "SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1", Cell & Bioscience, 12:36, DOI: 10.1186/s13578-022-00770-1, PMID: 35317858,
Abt, E.R., et al., (2022), "Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells", Cell Reports, 38:110236, DOI: 10.1016/j.celrep.2021.110236
Le-Trilling, Vu Thuy Khanh, et al. (2020). The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity. Cell Reports, 19 pgs. PMID: 32075763.
Raviram, Ramya, et al. (2018). Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate. Genome Biology, 19 pgs. PMID: 30541598.
Kativhu, Chido, et al. (2016). A Model to Explain How the Bacille Calmette Guerin (BCG) Vaccine Drives Interleukin-12 Production in Neonates. PLOS One, 12 pgs. PMID: 27571272.
Neufeldt, Christopher, et al. (2013). Hepatitis C Virus-Induced Cytoplasmic Organelles Use the Nuclear Transport Machinery to Establish an Environment Conducive to Virus Replication. PLOS Pathogens, 15 pgs. PMID: 24204278.
PBL Assay Science(又名:Pestka Biomedical Laboratories, Inc.)作为干扰素和细胞因子蛋白和抗体以及预包装的免疫测定试剂盒的高质量制造商而享有盛誉。生产和销售的高品质干扰素产品和生物标志物检测试剂盒在很多高影响力出版物中都有引用,并已在具有挑战性的样本中进行了外部验证。PBL Assay Science提供各种干扰素亚型的蛋白,抗体和检测试剂盒,如:IFN-Alpha(IFN-ɑ 2a,IFN-ɑ 2b,IFN-ɑ 5,IFN-ɑ 6,IFN-ɑ 7,IFN-ɑ 14,IFN-ɑ 16,IFN-ɑ 17......),IFN-Beta(IFN-β 1a,IFN-β 1b),IFN-Lambda(IFN-λ),IFN-Omega(IFN-ω),IFN-Gamma(IFN-γ)......艾美捷科技是PBL Assay Science的中国代理商,为科研工作者提供优质的产品与服务。
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