在生物医学研究和临床诊断中,免疫球蛋白M(IgM)是评估小鼠免疫状态的重要生物标志物。IgM是B细胞初次应答中产生的第一个抗体类别,对于识别和测量IgM水平,IgM (小鼠) ELISA试剂盒提供了一种高效、灵敏的解决方案。
货号:BGT-KET-109
抗体类型:ELISA
反应性:小鼠/鼠类
宿主:山羊
特异性/目标:IgM
大小:1.0
检测范围:25 ng/ml - 800 ng/ml
灵敏度:2.786 ng/ml
检测时间:100分钟
样本类型:血浆,血清
储存:2-8°C
IgM (小鼠) ELISA Kit检测原理:
组成和优势:
预包被的96孔板条,用于固定抗体
检测抗体,通常标记有酶,如辣根过氧化物酶(HRP)
酶底物,用于产生可测量的信号
标准品和校准曲线生成所需的试剂
详细的操作手册和数据分析指南
优势:
高灵敏度和特异性,确保结果的准确性
操作简便,适合高通量实验
试剂稳定性好,便于长期存储和使用
IgM (小鼠) ELISA Kit部分文献参考:
Publications citing ICL's Mouse IgM ELISA Kit:
Zhang S, Dubois W, Feng X, Nguyen JT, Young NS, Mock BA. Conditional deletion of mTOR discloses its essential role in early B-cell development. Mol Carcinog. 2022;61(4):408-416. doi:10.1002/mc.23386
Jessica M. Mayeux et al. Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse Front. Immunol., 26 April 2018 | https://doi.org/10.3389/fimmu.2018.00874
Mayeux JM, Escalante GM, Christy JM, Pawar RD, Kono DH, Pollard KM. Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse. Front Immunol. 2018;9:874. Published 2018 Apr 26. doi:10.3389/fimmu.2018.00874
Sharma NS, Lal CV, Li JD, et al. The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol. 2018;315(5):L653-L661. doi:10.1152/ajplung.00308.2017
Franz B et al. Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB Journal of Immunology Research Volume 2015 (2015), Article ID 840842, 13 pages
Zhang S, Pruitt M, Tran D, et al. B cell-specific deficiencies in mTOR limit humoral immune responses. J Immunol. 2013;191(4):1692-1703. doi:10.4049/jimmunol.1201767
Capoccia B et al. Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells Physiological Genomics Published 1 February 2011 Vol. 43 no. 3, 174-186 DOI: 10.1152/physiolgenomics.00084.2010
Santiago M et al. Innate Retroviral Restriction by Apobec3 Promotes Antibody Affinity Maturation In Vivo The Journal of Immunology July 15, 2010 vol. 185 no. 2 1114-1123
相关产品:
anti-Mouse IgM Antibody (Goat) - Affinity Purified
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