Bertin Bioreagent CGRP（大鼠）ELISA试剂盒在鼠免疫学研究中的应用潜力

降钙素基因相关肽 （CGRP） 是一种有效的血管扩张剂，还会引起许多其他生物学效应。据报道，正常受试者的平均血浆 CGRP 水平为 0.8 pmol/L 至 71 pmol/l（3 pg/mL 至 269 pg/mL）。在血液透析、怀孕、哮喘加重和甲状腺髓样癌病例中，循环 CGRP 水平升高。

作为Bertin Bioreagent全国总代理，艾美捷科技强烈推荐Bertin Bioreagent热销产品CGRP（大鼠）ELISA试剂盒。产品仅用于科研，不可用于临床诊断。

CGRP（大鼠）ELISA试剂盒：

文献参考：

PRODUCT EXPLANATION: ACETYLCHOLINESTERASE MARKER IN ENZYME-IMMUNOASSAYS

Grassi J., Pradelles P. Compounds labelled by the acetylcholinesterase of Electrophorus Electricus. Its preparation process and its use as a tracer or marquer in enzymo-immunological determinations. United States patent, N° 1,047,330. September 10, 1991

Grassi J., Pradelles P. The use of Acetylcholinesterase as a Universal marker in Enzyme-Immunoassays. Proceedings of the Third International Meeting on Cholinesterases, American Chemical Society (1991)

Pradelles P., Grassi J., Maclouf J. Enzyme Immunoassays of Eicosanoids Using Acetylcholinesterase. Methods in Enzymology (1990), vol. 187, 24-34

PRODUCT EXPLANATION: CGRP

Russell FA, King R, Smillie SJ et al. Calcitonin gene-related peptide: physiology and pathophysiology. Physiol Rev. 2014 Oct;94(4):1099-142

Schou WS, Ashina S, Amin FM et al. Calcitonin gene-related peptide and pain: a systematic review. J Headache Pain. 2017 Dec;18(1):34

PRODUCT EXPLANATION: CGRP KIT DEVELOPMENT

Frobert Y., Nevers M.-C., Amadesi S., Volland H., Brune P., Geppetti P., Grassi J. & Créminon C. A sensitive sandwich enzyme immunoassay for calcitonin gene-related peptide (CGRP): characterization and application. Peptide 20 (1999) 275-284

Valentin MA, Ma S, Zhao A, Legay F, Avrameas A. Validation of immunoassay for protein biomarkers: Bioanalytical study plan implementation to support pre-clinical and clinical studies. J Pharm Biomed Anal. (2011) 55(5) : 869-877

European Medicines Agency. Guideline on bioanalytical method validation, 21 July 2011

法国Bertin Technologies公司是一家大型仪器设备及试剂供应商，拥有50多年的历史，产品涉及卫生、环境、安全甚至军工等诸多领域。Bertin Bioreagent是Bertin Technologies集团的生物试剂部门，主要是致力于研发与炎症，氧化损伤，内分泌学，糖尿病，肥胖症，高血压，精神药理学，癌症，哮喘，朊病毒疾病，药代动力学和代谢等相关的化学试剂 ，蛋白，底物，抗体及检测试剂盒等产品。 Bertin Instruments是Bertin Technologies集团的仪器部门，其中旗舰产品Precellys系列多功能生物样品匀浆器是全世界各个实验室的明星产品，截至目前累计有15000+的引文！ 作为Bertin在中国的区域总代理，艾美捷科技有限公司将为中国客户提供全面的Bertin的产品。