- 中文名称
Poly泛素(Ubiquitin) (K63-linked) 单克隆抗体 (HWA4C4)
- 英文名字
- Polyubiquitin (K63-linked) monoclonal antibody (HWA4C4)
- 供应商
- Viva Bioscience
- 产品货号
- VB2888-25
- 产品报价
- ￥1375/25ug
- 产品说明书
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- 产品新闻
- 背景资料
- Modification of proteins by addition of K63-linked polyubiquitin chains is implicated in a variety of cellular events, including DNA repair, signal transduction and receptor endocytosis.
A monoclonal antibody (mAb) has been generated that specifically recognizes K63-linked polyubiquitin chains, but not any other isopeptide-linked (K6, K11, K27, K29, K33, or K48) polyubiquitin chain or monoubiquitin. The specificity of this K63-linked ubiquitinspecific monoclonal antibody was demonstrated using di-ubiquitin chains and with endogenously ubiquitinylated species in both cell lysates and intact cells.
The antibody has been extensively characterised by ELISA, one-dimensional Western blotting, immunofluorescence utilising cells transfected with wild type and [K63R]ubiquitin, and immunohistochemistry using material derived from the brains of humans suffering from a variety of neurodegenerative disease.
- 应用类型
- 免疫原
- Synthetic peptide containing the ubiquitin K63-isopeptide motif
- 来源宿主
- С
- 反应性
- 保存建议
- 其他
- Ӣ
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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