Ubiquitin modification of cellular proteins has been shown to be involved with a wide range of biochemical processes including proteasomal degradation, signal transduction, DNA repair, endocytosis and autophagy.
P4D1 is a widely used and cited ubiquitin monoclonal antibody, that detects ubiquitinated proteins (mono- and poly-ubiquitinated), ubiquitin chains and free ubiquitin.