A potent, selective, cell permeable and irreversible ATP-competitive inhibitor of the AAA-ATPase p97 / VCP, an ATPase associated with diverse cellular activities including autophagy and proteasomal degradation. Blocks ubiquitin-dependent protein degradation pathways. Proteasome and autophagy inhibitor.
产品描述
Irreversible, cell permeable inhibitor of p97. Autophagy inhibitor