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细胞分析试剂盒
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中文名称

血浆/血清循环和核外RNA纯化大提试剂盒(提取试剂盒)

英文名字
Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Slurry Format) (25)
供应商
Norgen Biotek
产品货号
NGB-50900
产品报价
¥询价/25Preps
产品说明书
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产品描述
Norgen’s Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Slurry Format) provides a fast, reliable and simple procedure for isolating circulating RNA and exosomal RNA from various amounts of plasma/serum ranging from 2 mL to 5 mL. Free-circulating RNA and exosomal RNA in plasma and serum has the potential to provide biomarkers for certain cancers and disease states, and includes tumor-specific extracellular RNA in the blood. Norgen’s Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Slurry Format) provides an efficient method for the purification of all sizes of these fragmented free-circulating RNAs and exosomal RNAs from human plasma or serum.Exosomes are 40 - 100 nm membrane vesicles, which are secreted by most cell types. Exosomes can be found in saliva, blood, urine, amniotic fluid and malignant ascitic fluids, among other biological fluids. Evidence has been accumulating recently that these vesicles act as cellular messengers, conveying information to distant cells and tissues within the body. The exosomes contain cell-specific proteins, lipids and RNAs, which are transported to other cells, where they can alter function and/or physiology. These exosomes may play a functional role in mediating adaptive immune responses to infectious agents and tumours, tissue repair, neural communication and transfer of pathogenic proteins. Recent work has demonstrated the presence of distinct subsets of microRNAs within exosomes which depend upon the tumour cell type from which they are secreted. For this reason exosomal RNAs may serve as biomarkers for various diseases including cancer. As the RNA molecules encapsulated within exosomes are protected from degradation by RNAses they can be efficiently recovered from biological fluids, such as plasma or serum.
产品特点
Isolate all sizes of circulating and exosomal RNA, including microRNA; Versatile plasma and serum input volumes (2 mL to 5 mL); Concentrate circulating and exosomal RNA into small elution volumes; Isolate inhibitor-free circulating and exosomal RNA; Bind and elute all RNA irrespective of size or GC content, without bias.
保存建议
所有缓冲液应密封保存,并在室温(15-25°C)下保存长达1年。具体保存情况收到产品后请按说明书存放。
其他
Norgen Biotek成立于1998年,公司总部位于加拿大,是一家著名全球化生物技术公司,基于专利的碳化硅膜纯化技术和无苯酚专利配方,生产高品质的核酸和蛋白质纯化及富集产品用于研究和诊断。Norgen Biotek 在2003年获得加拿大国家研究委员会颁发的科技创新奖,是一家致力于样品制备并获得ISO 9001(产品质量)、ISO 13485(产品可用于商业化的医疗设备,包括用于体外诊断领域)和ISO 15189(可用于临床检测机分子诊断领域的研发能力)认证的生物科技公司。 目前该公司的产品多达700余种,提供一流的样品制备试剂盒,应用于基因组和蛋白组等不同的领域。其产品主要覆盖包括各种标本类型的DNA,RNA和蛋白质的纯化富集,从活检样本(包括尿液,血浆,血清和血液)中纯化RNA和DNA,全系列的PCR试剂、缓冲液、分子量ladder和塑料过滤装置。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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