Leuprorelin （INN） or leuprolide acetate （USAN） is a gonadotropin-releasing hormone agonist （GnRH agonist）.
By causing constant stimulation of the pituitaryGnRH receptors， it initially causes stimulation （flare）， but thereafter decreases pituitary secretion （downregulation） of gonadotropins luteinizing hormone（LH） and follicle-stimulating hormone（FSH）.
Like other GnRH agonists， leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer， estrogen-dependent conditions （such as endometriosisor uterine fibroids）， to treat precocious puberty， and to control ovarian stimulation in IVF.
Leuprolide Human Synthetic is a single， non-glycosylated， polypeptide chain containing 9 amino acids and having a molecular mass of 1209 Dalton.
Lyophilized Leoprolide although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution Leuprorelin should be stored at 4℃ between 2-7 days and for future use below -18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.