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Human Follicle Stimulating Hormone
中文名称 【FSH】人卵泡刺激素
供应商 ProSpec 产品货号 HOR-249
产品报价 ¥1495/100IU   ¥3565/500IU   ¥6210/5000IU

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背景资料 Follicle stimulating hormone (FSH) is a hormone synthesised and secreted by gonadotropes in the anterior pituitary gland. FSH and LH act synergistically in reproductionIn women, in the ovary FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows it releases inhibin, which shuts off the FSH production.
In men, FSH enhances the production of androgen-binding proteinby the Sertoli cells of the testes and is critical for spermatogenesis.
In both males and females, FSH stimulates the maturation of germ cells. In females, FSH initiates follicular growth, specifically affecting granulosa cells. With the concomitant rise in inhibin B FSH levels then decline in the late follicular phase. This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase, there is a slight rise in FSH that seems to be of importance to start the next ovulatory cycle.
Like its partner, LH, FSH release at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone(GnRH). Those pulses, in turn, are subject to the estrogen feed-back from the gonads.
产品描述 FSH Human is a glycoprotein produced from urine of post-menopausal women and having a total molecular mass of 30,000 Dalton. FSH is a heterodimeric hormone consisting of 92 amino acids a chain and 111 amino acids b chain. The FSH is purified by proprietary chromatographic techniques.
来源宿主 Urine of post-menopausal women.
序列
溶解建议 提供的人卵泡刺激素产品为白色无菌冻干粉末,冻干粉里不含有其它添加剂.推荐使用无菌的18MΩ的超纯水来溶解,浓度不低于100ug/ml,便于后续稀释.
保存建议 Lyophilized FSH although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution FSH-beta should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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