Growth-hormone-releasing hormone （GHRH）， also known as growth-hormone-releasing factor （GRF or GHRF） or somatocrinin， is a 44-amino acidpeptide hormoneproduced in the arcuate nucleusof the hypothalamus.
GHRH is released from neurosecretory nerve terminals of these arcuate neurons， and is carried by the hypothalamo-hypophysial portal circulation to the anterior pituitary glandwhere it stimulates growth hormone（GH） secretion. GHRH also stimulates the production of GH. GHRH is released in a pulsatile manner， stimulating similar pulsatile release of GH. In addition， GHRH also promotes slow-wave sleepdirectly.
Growth Hormone Releasing Hormone Human Synthetic is a single， non-glycosylated， polypeptide chain containing 29 amino acids and having a molecular mass of 3358.9 Dalton.
Corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone consisting of 44 amino acid residues.
The GHRH is purified by proprietary chromatographic techniques.
The free base of sermorelin has the empirical formula
Lyophilized Growth Hormone Releasing Hormone although stable at room temperature for 3 weeks， should be stored desiccated below
-18℃. Upon reconstitution GHRF should be stored at 4℃ between
2-7 days and for future use below -18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.