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细胞分析试剂盒
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中文名称

Fractalkine, (CX3CL1), Flow Cytometry Kit, BioAssay (Human)

英文名字
Fractalkine, (CX3CL1), Flow Cytometry Kit, BioAssay (Human)
供应商
USBiological
产品货号
F6069-94
产品报价
¥1/1Kit
产品说明书
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产品新闻
背景资料
USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
产品描述
CX3CL1, also named neurotactin, is a novel chemokine recently identified through bioinformatics. CX3CL1 has a unique C-X3-C cysteine motif near the amino-terminus and is the first member of a fourth branch of the chemokine superfamily. Unlike other known chemokines, CX 3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. Human CX 3CL1 cDNA encodes a 397 amino acid (aa) residue membrane protein with a 24 aa residue predicted signal peptide, a 76 aa residue chemokine domain, a 241 aa residue stalk region containing 17 degenerate mucin-like repeats, a 19 aa residue transmembrane segment and a 37 aa residue cytoplasmic domain. The extracellular domain of human CX 3CL1 can be released, possibly by proteolysis at the dibasic cleavage site proximal to the membrane, to generate soluble CX 3CL1. CX3CL1 mRNA has been detected in various tissues including the brain and heart. The expression of CX 3CL1 was also reported to be up-regulated in endothelial cells and microglia by inflammatory signals. Membrane-bound CX 3CL1 has been shown to promote adhesion of leukocytes. The soluble chemokine domain of human CX 3CL1 was reported to be chemotactic for T cells and monocytes while the soluble chemokine domain of mouse CX 3CL1 was reported to chemoattract neutrophils and T-lymphocytes but not monocytes. The gene for human CX 3CL1 has been mapped to chromosome 16q (Pan, Y. et al., 1997, Nature 387:611; Bazan, J.F. et al., 1997, Nature 385:640; Mackay, C.R. 1997, Current Biology 7:R384).
产品特点
针对Fractalkine, (CX3CL1), Flow Cytometry Kit, BioAssay (Human)该产品的特点优势,欢迎查阅官网提供的产品说明书。
保存建议
建议收到Fractalkine, (CX3CL1), Flow Cytometry Kit, BioAssay (Human)产品后将其置于4°C保存。
其他
Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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