IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production,and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine,and thus negatively regulate its biological activity.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达
溶解建议
提供的大鼠白介素-18(rIL 18)产品为过滤灭菌的白色冻干粉末;该冻干粉末是从含1mg/ml大鼠白介素-18(rIL 18)的0.4 x PBS pH 7.2溶液中冻干产生的.我们建议加无菌的18MΩ-cm水以配制工作储存液到100ug/ml,后继实验过程中可根据实验要求进一步稀释.