IGFBP3 is a member of the insulin-like growth factor binding protein （IGFBP） family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit （IGFALS） and either insulin-like growth factor （IGF） I or II. In this form，it circulates in the plasma，prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants，encoding different isoforms，have been characterized.
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大肠杆菌中重组表达
溶解建议
提供的人胰岛素样生长因子结合蛋白-3（IGFBP 3）产品为过滤灭菌的白色冻干粉末；该冻干粉末是从含人胰岛素样生长因子结合蛋白-3（IGFBP 3）的20mM Tris HCL溶液中冻干产生的.我们建议加无菌的18MΩ-cm水以配制工作储存液到100ug/ml，后继实验过程中可根据实验要求进一步稀释.
