Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). It is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.
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来源宿主
大肠杆菌中重组表达
溶解建议
提供的重组小鼠生长调节致癌基因α(CXCL1), His标签产品为无菌的无色溶液形式.
保存建议
整瓶保存于4℃时,应在2-4周用完.长期保存应置于-20℃.
长期保存,推荐添加载体蛋白 (0.1% HSA or BSA).
请避免反复冻融.