Zacopride hydrochloride is a derivative of benzamide, described as a potent 5-HT3 receptor antagonist with 5-HT4 receptor agonistic properties. Zacopride is a recemic compound. Studies showed that the S(-) form has a higher binding affinity for central and peripheral 5-HT3 recertor compared to R(+) zacopride. Ki values for 5-HT3 and 5-HT4 receptors are 0.38 nM and 373 nM recpectively.
产品描述
A Potent Antagonist of 5-HT3 Receptors and an Agonist of 5-HT4 Receptors
产品形式
Zacopride hydrochloride is a derivative of benzamide, described as a potent 5-HT3 receptor antagonist with 5-HT4 receptor agonistic properties. Zacopride is a recemic compound. Studies showed that the S(-) form has a higher binding affinity for central and peripheral 5-HT3 recertor compared to R(+) zacopride. Ki values for 5-HT3 and 5-HT4 receptors are 0.38 nM and 373 nM recpectively.