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中文名称

盐酸氟西汀(50毫克)

英文名字
Fluoxetine hydrochloride
供应商
Alomone
产品货号
ALO-F-155-50
产品报价
¥已停产
产品说明书
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产品新闻
背景资料
Fluoxetine hydrochloride (Prozac, Sarafem) is a synthetic high affinity KV4.3 blocker and is also a competitive 5-HT reuptake inhibitor. Fluoxetine has an effective concentration of 5-300 μM with an IC50 of 11.8 μM on cloned KV4.3 channels. Fluoxetine mostly interacts with the open state of KV4.3 and blocks the channel in a concentration, time, voltage and use-dependent manner with steady state currents being more affected than the peak current. Similarly, Fluoxetine blocks other channels such as delayed rectifier and A-type KV channels. Fluoxetine is widely used for the treatment of general anxiety disorder (GAD) but also for other clinical conditions such as neuropathic pain, obesity and premenstrual dysphoric disorder. Despite its usually safe user profile it has been linked with hematological side effects that include life threatening conditions, one of them being intracranial bleeding. Although extensive research of Fluoxetine has been conducted the pharmacological mechanisms behind its various therapeutic effects are not yet fully understood.
产品描述
A Blocker of KV4.3 Channels and a Competitive Inhibitor of 5-HT Re-Uptake
产品形式
KV4 channel complexes also known as Shal-type K+ channels are expressed in a variety of tissues, with particularly high levels in the brain and heart .nSerotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter synthesized from the amino acid tryptophan by the enzyme tryptophan-decarboxylase.
保存建议
艾美捷为您提供的Alonmone Labs原装进口的Fluoxetine hydrochloride (50 mg)产品可室温运输,建议您在收到产品后将其置于合适的温度下保存。
其他
Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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