µ-Conotoxin GIIIB was originally isolated from the marine snail Conus geographus and this is a synthetic version of the peptide. µ-Conotoxin GIIIB selectively blocks Nav1.4 channels which are expressed predominantly in muscle. It is a potent blocker and 600 nM completely blocked Nav1.4 related currents in rat skeletal muscle.
产品描述
A Selective Blocker of Skeletal Muscle NaV1.4 Channels
产品形式
µ-Conotoxin GIIIB was originally isolated from the marine snail Conus geographus and this is a synthetic version of the peptide. µ-Conotoxin GIIIB selectively blocks Nav1.4 channels which are expressed predominantly in muscle. It is a potent blocker and 600 nM completely blocked Nav1.4 related currents in rat skeletal muscle.