Bupivacaine hydrochloride is a local anesthetic of the amino amide group. Drugs of this category induce their effect by binding to the intracellular area of the Na+ channel, which blocks the channel's ability to allow Na+ to enter the nerve cell, and thus preventing the cell's depolarization.
产品描述
A State-Dependent Blocker of Neuronal NaV Channels and a Blocker of KCa Channels
产品形式
Voltage-gated Na+ channels (NaV) are plasma membrane protein complexes which allow the passage of Na+ ions into cells following a change in the transmembrane voltage.nNaV channels are primarily expressed in the central nervous system.