- 中文名称
CaVBeta1抗体(50 ul)
- 英文名字
- Anti-CaVBeta1
- 供应商
- Alomone
- 产品货号
- ALO-ACC-106-50
- 产品报价
- ¥已停产
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- CaVβ subunits play critical roles in membrane trafficking of the channel complex and regulation of voltage-dependent gating. The CaVβ subunit binds to the endoplasmic reticulum (ER) retention signal in the I-II loop of the α1-subunit, which allows channels to traffic to the surface membrane4. Furthermore, CaVβ subunits not only allow for membrane trafficking of the channel complex, they also can play a role in determining the subcellular localization of channels on the surface membrane5. There are four distinct CaVβ subunits CaVβ1, CaVβ2, CaVβ3 and CaVβ4.n Three splice variants exist for the β1 subunit: β1a, β1b and β1c. β1a is known to be expressed in skeletal muscle and brain, but not in smooth muscle or heart. β1a appears to be important for the functional expression of the α1 subunit in skeletal muscle7. β1b was identified by cloning in rat brain, heart and hippocampus, and differs from β1a by having a deletion of ~50 amino acids at residue 209, and having a 120-residue C-terminal elongation. β1c was cloned from human heart and hippocampus and has the same deletion as β1b, but lacks the C-terminal extension.
- 应用类型
- 经验证,该抗体可应用于IH、WB等实验应用,也可用于 IC、IP等实验。
- 免疫原
- CaVBeta1抗体的免疫原肽段为(C)DRATGEHASVHEYPGE。此免疫原序列来源于456-471 位氨基酸残基,该序列来源于大鼠CaVβ1 (Accession编号为P54283)。胞内, adjacent to the C端
- 来源宿主
- 兔
- 反应性
- 反应性:小鼠、 大鼠、也可反应于: 人
- 保存建议
- 艾美捷为您提供的CaVBeta1抗体(50 ul)为室温运输,建议您收到产品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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