A potent cardiotoxin, which evokes a positive inotropic and chronotropic effect on mammalian heart muscle. Recently it was found that this toxin modifies the current passing through the fast Na+ channel in neuroblastoma cells, leading to delay and incomplete inactivation. n Effective at concentrations of 1-5 nM in isolated guinea-pig atria.
产品描述
A Potent Activator of NaV Channels
产品形式
A potent cardiotoxin, which evokes a positive inotropic and chronotropic effect on mammalian heart muscle. Recently it was found that this toxin modifies the current passing through the fast Na+ channel in neuroblastoma cells, leading to delay and incomplete inactivation. n Effective at concentrations of 1-5 nM in isolated guinea-pig atria.