英文名字 Acetylbenzoylaconine
中文名称 Acetylbenzoylaconine (10 mg)
供应商 Alomone
产品货号 ALO-A-150-10
产品报价 ¥规格或产品已更新
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产品新闻
背景资料 Aconitine is diterpense two-ester alkaloid derived from the tubers of aconitinum plants and has been used as traditional herbal medicine in China and Japan since ancient time. Modern pharmacologic studies have shown that aconitine has effects of analgesia and anesthesia, anti inflammatory, immune regulation, anti tumor and cardiotonic actions . At the same time, aconitine also presents enormous toxicity . It is well known for its toxic effects on the heart and central nervous system where it causes cardiac arrhythmias, systemic paralysis and coma. Aconitine alters the kinetics and voltage dependence of Na+ channel activation, inhibits Na+ channel inactivation through binding to neurotoxin receptor site 2 and causes persistent activation of Na+ channels at the resting membrane potential.
产品描述 An Activator of NaV Channels
产品形式 Voltage-gated sodium channels (NaV) are present in most excitable cell membranes and play an important role in generating action potentials. A variety of toxins and chemicals are known to either block or modulate Na+ channels and have proven to be invaluable in investigating the physiological characteristics of these channels. Most notably, tetrodotoxin (TTX), a potent and selective blocker of Na+ channels binds to neurotoxin receptor site 1 to block them.
产品说明书
其他 Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

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