TRAP1 encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. TRAP1 (TNF Receptor Associated Protein 1) is a Protein Coding gene. Diseases associated with TRAP1 include Cakut With Or Without Vacterl and Vacterl Association. Among its related pathways are Metabolism and Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF).