The protein encoded by HMX2 is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing HMX2 have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. HMX2 (H6 Family Homeobox 2) is a Protein Coding gene. Diseases associated with HMX2 include Cecal Benign Neoplasm and Cecum Adenocarcinoma.