The protein encoded by GNL3 may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for GNL3. GNL3 (G Protein Nucleolar 3) is a Protein Coding gene. Among its related pathways are Ribosome biogenesis in eukaryotes and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers.