CLASP2 (Cytoplasmic Linker Associated Protein 2) is a Protein Coding gene. Diseases associated with CLASP2 include Clostridium Difficile Colitis. Among its related pathways are DNA Damage and Cell Cycle, Mitotic. Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules . Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell.This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.