- 中文名称
L型电压依赖型钙通道β4 多克隆抗体
- 英文名字
- CACB4 Polyclonal Antibody
- 供应商
- 艾美捷
- 产品货号
- ABP57958
- 产品报价
- ￥替代产品
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- CACNB4 (Calcium Voltage-Gated Channel Auxiliary Subunit Beta 4) is a Protein Coding gene. Diseases associated with CACNB4 include Episodic Ataxia, Type 5 and Epilepsy, Idiopathic Generalized 9. Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and Fc-GammaR Pathway. CACNB4 encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in CACNB4 have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5.
- 应用类型
- WB、ELISA
- 免疫原
- 合成多肽：来源于人员源 CACB4 蛋白，氨基酸序列为：160-240
- 来源宿主
- 兔
- 反应性
- 人、小鼠
- 保存建议
- 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
- 其他
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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