TNIP2 encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to TNIP2 is located on the X chromosome TNIP2 (TNFAIP3 Interacting Protein 2) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Activated TLR4 signalling.