SERPINA3 (Serpin Family A Member 3) is a Protein Coding gene. Diseases associated with SERPINA3 include Endometrial Adenosquamous Carcinoma and Alpha 1-Antitrypsin Deficiency. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. ease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.