IRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.蛋白别名为:IRS1; Insulin receptor substrate 1; IRS-1;基因ID为:3667;蛋白质ID:P35568
应用类型
IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human IRS-1 around the non-phosphorylation site of S323.