omeobox D genes located on chromosome 2. The homeobox D10 functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.蛋白别名为:HOXD10; HOX4D; HOX4E; Homeobox protein Hox-D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E;基因ID为:3236;蛋白质ID:P28358
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human HoxD10. at AA rangle: 260-340