The amyloid beta precursor protein binding family B member 2 encoded by APBB2 interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. 蛋白别名为:APBB2; FE65L; FE65L1; Amyloid beta A4 precursor protein-binding family B member 2; Protein Fe65-like 1;基因ID为:323;蛋白质ID:Q92870
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Fe65L. at AA rangle: 440-520