Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. Myeloperoxidase produces hypohalous acids central to the microbicidal activity of neutrophils.蛋白别名为:MPO; Myeloperoxidase; MPO;基因ID为:4353;蛋白质ID:P05164
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human MPO 89k. at AA rangle: 40-120