This gene product JAK2 （Janus kinase 2） is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for JAK2 exhibit embryonic lethality associated with the absence of definitive erythropoiesis.蛋白别名为：Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2);基因ID为：3717；蛋白质ID:O60674
