- 中文名称
【CD62E】人源细胞表达的重组人CD62E / E-选择素(20 ug)
- 英文名字
- Human CellExp CD62E/E-Selectin, human recombinant
- 供应商
- Biovision
- 产品货号
- 7434-20
- 产品报价
- ¥已停产
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- E-Selectin, also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), a member of the Selectin family, is a 107-115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1β and TNFα. E selectin has a cassette structure: an N-terminal, C-type lectin domain, an EGF (epidermal-growth-factor)-like domain, 6 Sushi domain (SCR repeat) units, a transmembrane domain (TM) and an intracellular cytoplasmic tail (cyto). During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. The local release of cytokines IL-1 and TNF-α by damaged cells induces the over-expression of E-selectin on endothelial cells of nearby blood vessels. E-selectin mediates the adhesion of tumor cells to endothelial cells, by binding to E-selectin ligands expressed by neutrophils, monocytes, eosinophils, memory-effector T-like lymphocytes, natural killer cells or cancer cells. Furthermore, a number of studies have reported that levels of E-Selectin may be elevated in subjects with a variety of pathological conditions.
- 序列
- 人源细胞表达的重组人CD62E/E-选择素蛋白产品,又称SELE, RP1-117P20.2, CD62E, ELAM1, ESEL, LECAM2, E-Selectin.其对应NCBI基因号为6401,对应Accession号为P16581.
- 来源宿主
- 提供的【CD62E】人源细胞表达的重组人CD62E/E-选择素产品的来源为人胚肾HEK293细胞重组表达重组表达.
- 溶解建议
- 人源细胞表达的重组人CD62E/E-选择素产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
- 保存建议
- 在您收到艾美捷发出的【CD62E】人源细胞表达的重组人CD62E/E-选择素产品后,建议将其置于-20°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的Leader,BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.
- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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