- 中文名称
【钙黏着蛋白1】人源细胞表达的重组人E-钙粘蛋白/ ECAD /钙粘蛋白-1 / CD324蛋白(25 ug)
- 英文名字
- Human CellExp E-Cadherin /ECAD /Cadherin-1/CD324 Protein, human recombinant
- 供应商
- Biovision
- 产品货号
- 7420-25
- 产品报价
- ¥已停产
- 产品说明书
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- 产品新闻
- 背景资料
- Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. Cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-1 (CDH1) also known as epithelial cadherin (E-cadherin), CD_antigen (CD324), Uvomorulin (UVO) ECAD and CDHE, CDH1 / CD324 contains 5 cadherin domains. CDH1 / CD324 / ECAD is expressed in non-neural epithelial tissues. CDH1 / E-CAD is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad promotes non-amyloidogenic degradation of Abeta precursors and has a strong inhibitory effect on APP C99 and C83 production. Defects in CDH1 / CD324 / ECAD are the cause of hereditary diffuse gastric cancer (HDGC).
- 序列
- 人源细胞表达的重组人E-钙粘蛋白/ECAD/钙粘蛋白-1/CD324 Protein蛋白产品,又称Cadherin-1, CDH1, CD324, E-cadherin, Arc-1, ECAD, LCAM, UVO.其对应NCBI基因号为999,对应Accession号为P12830.
- 来源宿主
- 提供的【Cadherin 1】人源细胞表达的重组人E-钙粘蛋白/ECAD/钙粘蛋白-1/CD324 Protein产品的来源为人胚肾HEK293细胞重组表达重组表达.
- 溶解建议
- 人源细胞表达的重组人E-钙粘蛋白/ECAD/钙粘蛋白-1/CD324 Protein产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
- 保存建议
- 在您收到艾美捷发出的【Cadherin 1】人源细胞表达的重组人E-钙粘蛋白/ECAD/钙粘蛋白-1/CD324 Protein产品后,建议将其置于-20°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的Leader,BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.
- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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