- 中文名称
【IL31】再生人白介素-31(1毫克)
- 英文名字
- IL-31, human recombinant
- 供应商
- Biovision
- 产品货号
- 4983-1000
- 产品报价
- ¥已停产
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- IL-31 produced by activated Th2-type T cells, cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is constitutively expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. IL-31 is involved in the itching sensation and endorses the scratching behavior in NC/Nga mice with atopic dermatitis. IL-31 expression is connected with CLA(+) T cells and contributes to the development of atopic dermatitis-induced skin inflammation and pruritus. IL-31 is a powerful inducer of proinflammatory mediators in human colonic SEMFs. IL-31 takes part as a proinflammatory cytokine derived from Th2 cells. Serum IL-31 level is higher in patients with atopic dermatitis. IL-31 is involved in a broad range of immune- & non-immune cells & possesses potential pleiotropic physiological functions, including regulating hematopoiesis & immune response, causing inflammatory bowel disease, airway hypersensitivity & dermatitis. IL-31 human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids (24-164 a.a.) and having a molecular mass of 15.8 kDa.
- 序列
- 重组人白介素-31蛋白产品,又称Interleukin 31, IL31, IL-31.其对应NCBI基因号为386653,对应Accession号为Q6EBC2.
- 来源宿主
- 提供的【IL31】重组人白介素-31产品的来源为大肠杆菌重组表达.
- 溶解建议
- 重组人白介素-31产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration ≥ 100 ug/ml. This solution can then be diluted into other aqueous buffers.
- 保存建议
- 在您收到艾美捷发出的【IL31】重组人白介素-31产品后,建议将其置于-20°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的Leader,BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.
- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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